The Mangostan Revolution

Mangostan - The Queen of all Fruits.

Used for decades as an traditional health source.

Mangostan is very high on Xanthones - an Antioxidant

Antioxidant Power of Xanthones

A powerful antioxidant, xanthones are a family of vigorous phytonutrients.
Research supports the role of xanthones in minor muscle pain, immune system support, joint flexibility and intestinal health.*

Previous studies and ongoing research recognize xanthones for the following benefits:

• Bolstering of the cell’s defense against free radicals in the body and maintenance of cell integrity.9-12*
  
• Support of a healthy immune system.4, 6-8*
  
• Support of cartilage and joint function and flexibility.13-16*
  
• Maintenance of intestinal flora and regularity as well as support ofintestinal health.1-5*
  
• Maintenance of a healthy seasonal respiratory system.14*

For more information on xanthone research please visit www.thewholefruit.com

Nature's Greatest Xanthone Source

The mangosteen fruit, or Garcinia mangostana, is found primarily in Southeast Asia. The mangosteen fruit is composed of the rind (skin of the fruit), the pulp (four to eight segments) and the seeds (usually two to three seeds). Studies show the mangosteen is nature’s greatest supply of xanthones, the highest concentration of which resides in the fruit’s pericarp, which includes the rind and the pulp. According to research, the mangosteen including the pericarp, as found in XanGo Juice, is the source of close to 40 different xanthones.

The pericarp of the mangosteen has been used traditionally for centuries as an herbal preparation. Though the fruit also was touted for its biological properties, its divine taste made the mangosteen venerated.

Numerous independent investigators have researched and reported on the benefits of the mangosteen.

XanGo Juice: A New Category of Supplements is Born

Recognized as a category creator, XanGo Juice is a delicious dietary supplement that harnesses the nutritional attributes of the whole mangosteen fruit through a proprietary formula.

Made from an exclusive puree of the complete mangosteen fruit, XanGo Juice is a concentrated source of xanthones. Research shows xanthones possess potent antioxidant properties that may help achieve a healthy seasonal respiratory system, boost immune-system health, promote joint flexibility and maintain intestinal health.*

Through its exclusive whole-fruit mangosteen puree process, XanGo captures the benefits of the entire fruit in its market-leading XanGo Juice. XanGo’s founders referenced decades of mangosteen studies to support their discovery of a singular dietary mangosteen supplement with a sensational taste. One to three ounces each day is recommended to unleash the power of xanthones in XanGo Juice.


The Research

1. Begum N, Gopalakrishnan C, Subramanian S, Shankaranarayanan D, Kameswaran L. Anti-ulcer and anti microbial activities of Gartanin, a xanthone from Garcinia Mangostana Linn. . Bull Islam. 1982;2(20):518-521

2. Caius J. The Medicinal and Poisonous Plants of India. Jodhpur, India: Scientific Publishers; 1986.

3. Garnett M, Sturton S. G. mangostana in the treatment of amoebic dysentery. Chines Med J. 1932;46(10):969-973

4. Chopra R, Nayar S, Chopra I. Glossary of Indian Medicinal Plants. New Delhi; 1956.

5. Kirtikar K, Basu B. Indian Medicinal Plants. Vol 1. Dehra Dun, India: International Book Distributors; 1999.

6. Chanarat P, Chanarat N, Fujihara M, Nagumo T. Immunopharmacological activity of polysaccharide from the pericarp of mangosteen garcinia: phagocytic intracellular killing activities. Journal of the Medical Association of Thailand - Chotmaihet thangphaet J Med Assoc Thai. 1997/09// 1997;80 Suppl 1:S149-154.

7. Chen SX, Wan M, Loh BN. Active constituents against HIV-1 protease from Garcinia mangostana. Planta Med. 1996/08// 1996;62(4):381-382.

8. Gopalakrishnan G, Banumathi B, Suresh G. Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives. J Nat Prod. 1997/05// 1997;60(5):519-524.

9. Mahabusarakam W, Proudfoot J, Taylor W, Croft K. Inhibition of lipoprotein oxidation by prenylated xanthones derived from mangostin. Free Radic Res. 2000/11// 2000;33(5):643-659.

10. Williams P, Ongsakul M, Proudfoot J, Croft K, Beilin L. Mangostin inhibits the oxidative modification of human low density lipoprotein. Free Radic Res. 1995/08// 1995;23(2):175-184.

11. Yoshikawa M, Harada E, Miki A, et al. Antioxidant constituents from the fruit hulls of mangosteen. Yakugaku Zasshi. 1994;114(2):129-133.

12. Leong L, Shui G. An investigation of antioxidant capacity of fruits in Singapore markets. Food Chemistry. 2002;76:69-75.

13. Nabandith V, Suzui M, Morioka T, et al. Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. Asian Pac J Cancer Prev. 2004;5(4):433-438.

14. Nakatani K, Atsumi M, Arakawa T, et al. Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biol Pharm Bull. 2002/09// 2002;25(9):1137-1141.

15. Nakatani K, Nakahata N, Arakawa T, Yasuda H, Ohizumi Y. Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells. Biochem Pharmacol. 2002/01/01/ 2002;63(1):73-79.

16. Nakatani K, Yamakuni T, Kondo N, et al. gamma-Mangostin inhibits inhibitor-kappaB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells. Mol Pharmacol. 2004;66(3):667-674.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.